業績 - 東京科学大学循環器内科

2026年ゲノム・バイオマーカー不整脈・アブレーション

Rare coding variant architecture and gene discovery from 130,000 sequenced cases of atrial fibrillation.

Jurgens SJ, Enzan N, Dinsmore IR, Choi SH, Luo J, Lipov A, Hartle C, Wang X, Marston NA, Weng LC, Melloni GE, Chalazan B, Gray MP, Pirruccello JP, Diaz A, Chaffin MD, Ornelas-Loredo A, Tang O, Darbar FA, Kany S, Chen Y, von Falkenhausen AS, Morrison AC, Natale A, Tveit A, Geelhoed B, Cade B, Van Wagoner DR, Haase D, Soliman EZ, Davogustto GE, Calkins H, Anderson JL, Brody JA, Barnard J, Hokanson JE, Smith JD, Bis JC, Young K, Johnson LS, Long L, Risch L, Gula LJ, Kwee LC, Kühne M, Preuss M, Gupta N, Nafissi NA, Smith NL, Nilsson PM, van der Harst P, Wells QS, Judy RL, Schnabel RB, Johnson R, Smit RA, Gabriel S, Knight S, Furukawa T, Min YI, Yoneda ZT, Laksman ZW, Alonso A, Psaty BM, Albert CM, Arking DE, Roden DM, Chasman DI, Rader DJ, Conen D, McManus DD, Fatkin D, Boerwinkle E, Marcus GM, Christophersen IE, Smith JG, Roberts JD, Raffield LM, Shoemaker MB, Cho MH, Cutler MJ, Chung MK, Olesen MS, Sinner MF, Sotoodehnia N, Kirchhof P, Loos RJ, Nazarian S, Mohanty S, Damrauer SM, Kaab S, Heckbert SR, Redline S, Shah SH, Tanaka T, Ebana Y, Lubitz SA, Lunetta KL, Benjamin EJ, Rienstra M, Figtree GA, Darbar D, Bezzina CR, Ruff CT, Sabatine MS, Mirshahi T, Ellinor PT

Res Sq. 2026 May

DOI: 10.21203/rs.3.rs-9191644/v1 PMID: 42147184

2026年不整脈・アブレーション

Simultaneous Tricuspid Valve Replacement and Left Bundle Branch Area Pacing With Surgical Lead Refixation.

Goto K, Miyazaki S, Usui A, Sakurai H, Nagaoka E, Fujita T, Sasano T

Pacing Clin Electrophysiol. 2026 May:pace.70292

DOI: 10.1111/pace.70292 PMID: 42125939

2026年

Sex differences in circulating microRNA profiles in heart failure with preserved and reduced ejection fraction.

Numata G, Nakamura S, Tokiwa H, Taguchi A, Toyoda M, Kohno T, Maki H, Shiraishi Y, Takeuchi S, Goda A, Daigo K, Yamamoto N, Adachi Y, Yabe K, Kato T, Hiroi Y, Kato N, Kawahara T, Ueda K, Amiya E, Hatano M, Fujita H, Ieda M, Sasano T, Takeda N, Kohro T, Hirota Y, Komuro I, Wada Y, Takimoto E

Eur Heart J Open. 2026 May;6(3):oeag073

DOI: 10.1093/ehjopen/oeag073 PMID: 42282063

2026年不整脈・アブレーション

Association between baseline haptoglobin and early renal injury after pulsed-field ablation.

Tanaka Y, Takahashi A, Yano H, Kawaguchi N, Nakashima E, Okubo K, Hikita H, Sasano T

Heart Rhythm. 2026 May

DOI: 10.1016/j.hrthm.2026.05.026 PMID: 42190927

2026年

Standardized parallel pace-capture testing as a functional endpoint for lesion validation.

Nakamura S, Takigawa M, Kato R, Kawamura I, Honda M, Tateishi R, Negishi M, Goto K, Nishimura T, Yamao K, Tao S, Suzuki S, Iwanaga T, Miyazaki S, Sasano T

Heart Rhythm. 2026 May

DOI: 10.1016/j.hrthm.2026.05.028 PMID: 42190928

2026年試験デザイン

Efficacy and safety of a novel size-adjustable cryoballoon vs conventional cryoballoon: Results from the CONTRAST-CRYO II randomized clinical trial.

Inamura Y, Miyazaki S, Nitta J, Nakamura K, Kobori A, Inaba O, Murakami M, Nakamura T, Sekiguchi Y, Sasaki T, Sasaki Y, Mizuno S, Asano S, Naito S, Ooka J, Ohya H, Negishi M, Hirakawa A, Sasano T

Heart Rhythm. 2026 May

DOI: 10.1016/j.hrthm.2026.05.037 PMID: 42203054

2026年冠動脈・PCI

Two-Year Outcomes of Optical Coherence Tomography-Guided Percutaneous Coronary Intervention Stratified by Underlying Causes of Acute Coronary Syndrome.

Yamamoto MH, Mizukami T, Mori H, Kobayashi N, Takano M, Kondo S, Sugiyama T, Kakuta T, Wakabayashi K, Suwa S, Dohi T, Suzuki H, Kimura S, Yamaguchi M, Nakamura S, Naganuma T, Higuma T, Yamaguchi J, Yonetsu T, Ikari Y, Yamashita J, Kondo T, Honye J, Ashikaga T, Ochiai M, Mitsumata K, Yasuhara S, Otake H, Hibi K, Nanasato M, Shinke T

Can J Cardiol. 2026 May

DOI: 10.1016/j.cjca.2026.05.017 PMID: 42217734

2026年不整脈・アブレーション

Neurocognitive Function, Cerebral Blood Flow, and Hippocampal Volume After Catheter Ablation of Atrial Fibrillation.

Yamamoto T, Takahashi Y, Takagi S, Kitabayashi R, Ishii S, Sugihara G, Oyama J, Miyazaki S, Goya M, Hirakawa A, Takahashi H, Sasano T

JACC Clin Electrophysiol. 2026 May;12(5):1076-1085

DOI: 10.1016/j.jacep.2025.12.037 PMID: 41686112

2026年冠動脈・PCI画像診断

Complexity Within Complexity: Defining the Anatomic Sweet Spot for OCT-Guided PCI.

Yonetsu T

JACC Asia. 2026 May

DOI: 10.1016/j.jacasi.2026.04.007 PMID: 42246895

2026年ゲノム・バイオマーカー不整脈・アブレーション

Genetic variants and polygenic risk scores associated with paroxysmal atrial fibrillation in the Japanese population.

Shiomi M, Nagata Y, Sudo T, Takahashi K, Higuchi C, Ihara K, Asada K, Tanaka Y, Yamauchi Y, Sasaki T, Hachiya H, Imai Y, Fujita H, Sasano T, Furukawa T, Tanaka T

PLoS One. 2026 5;21(5):e0344360

DOI: 10.1371/journal.pone.0344360 PMID: 42081549

2026年画像診断

Virtual Noncontrast Images Derived From Photon-Counting CT Enhance Inter-Reader Reproducibility of Myocardial ECV Measurement in Patients With Cardiac Devices.

Yamakami Y, Hirasawa K, Hada H, Takahashi K, Tsunoda T, Ohmori M, Kanno Y, Yonetsu T, Sasano T

J Comput Assist Tomogr. 2026 May

DOI: 10.1097/rct.0000000000001880 PMID: 42200463

2026年不整脈・アブレーション

Distal Magnetic Sensors Eliminate Geometric Inaccuracy and Accelerate Mapping: A Preclinical Validation of a Novel Grid-Style Catheter.

Kato R, Takigawa M, Kawamura I, Honda M, Negishi M, Tateishi R, Iwakawa H, Yamao K, Goto K, Nishimura T, Tao S, Sayaka Suzuki DVM, Iwanaga T, Miyazaki S, Watanabe H, Sasano T

J Cardiovasc Electrophysiol. 2026 Apr;37(4):854-858

DOI: 10.1111/jce.70284 PMID: 41656185

2026年

Outpatient Cardiac Rehabilitation and Long-Term Clinical Outcomes After Transcatheter Aortic Valve Replacement.

Takegawa K, Iwanaga Y, Kanaoka K, Chishaki-Kawabata S, Matsuura H, Sasano T, Nishioka Y, Myojin T, Noda T, Imamura T, Miyamoto Y

J Am Geriatr Soc. 2026 Apr;74(4):1071-1079

DOI: 10.1111/jgs.70356 PMID: 41714308

2026年不整脈・アブレーション

Incidence and Predictors of Cardiac Tamponade in Contemporary Thermal Catheter Ablation of Atrial Fibrillation.

Murata K, Miyazaki S, Nitta J, Inaba O, Takahashi A, Yamashita S, Yamauchi Y, Nagata Y, Mizukami A, Takahashi Y, Iwai S, Hachiya H, Ono Y, Okada H, Suzuki A, Suzuki M, Handa K, Sasano T

J Cardiovasc Electrophysiol. 2026 Apr;37(4):796-800

DOI: 10.1111/jce.70299 PMID: 41725208

2026年不整脈・アブレーション冠動脈・PCI画像診断

Extensive coronary venous system mapping for outflow tract ventricular arrhythmias: Utility of a dual over-the-wire microelectrode catheter technique.

Shirai Y, Miyazaki S, Horie T, Kaneko M, Nagata Y, Murata K, Sagawa Y, Yamauchi Y, Tateishi R, Kawamura I, Goto K, Nishimura T, Tao S, Takigawa M, Nakata T, Tahara T, Hara S, Sato Y, Miwa N, Kusa S, Hachiya H, Yagishita A, Hayasaka K, Doi J, Yamashita S, Sasaki T, Kamata T, Kawabata M, Okishige K, Hirao K, Sasano T

Heart Rhythm. 2026 Apr

DOI: 10.1016/j.hrthm.2026.03.1951 PMID: 41933634

2026年症例報告

Late dislodgement of a residual functional atrial lead 4 years after ventricular lead extraction: A case report.

Arai R, Kawamura I, Tao S, Takigawa M, Miyazaki S, Sasano T

HeartRhythm Case Rep. 2026 Apr;12(4):445-449

DOI: 10.1016/j.hrcr.2026.01.006 PMID: 42028088

2026年画像診断

Paced QRS morphology and lead location in left bundle branch area pacing assessed by photon-counting cardiac computed tomography.

Goto K, Miyazaki S, Negishi M, Honda M, Tateishi R, Kawamura I, Nishimura T, Yamao K, Tao S, Takigawa M, Sasano T

Heart Rhythm. 2026 Apr

DOI: 10.1016/j.hrthm.2026.03.1945 PMID: 41932670

2026年

Relationship of atherosclerotic lesion by optical coherence tomography with cholesterol efflux capacity by immobilized liposome-bound gel beads method.

Miyakoshi T, Horiuchi Y, Araki M, Yonetsu T, Watanabe M, Kameda T, Yoshimoto A, Ichimura N, Tohda S, Tozuka M, Sasano T, Ohkawa R

Atherosclerosis. 2026 Apr:120724

DOI: 10.1016/j.atherosclerosis.2026.120724 PMID: 41963144

2026年不整脈・アブレーション画像診断症例報告

Photon-Counting Detector Computed Tomography Depicts a Ventricular Tachycardia Substrate: Periaortic Septal Intramural Late Iodine Enhancement.

Tateishi R, Nishimura T, Tao S, Yokoyama K, Hada H, Miyazaki S, Sasano T

JACC Case Rep. 2026 Apr;31(15):107250

DOI: 10.1016/j.jaccas.2026.107250 PMID: 41823901

2026年症例報告

Ischaemic cardiomyopathy with a significant improvement in left ventricular wall motion following revascularization for a honeycomb-like structure of the left anterior descending artery: a case report.

Yoshikawa H, Hanyu Y, Onishi Y, Yonetsu T, Sasano T

Eur Heart J Case Rep. 2026 Apr;10(4):ytag265

DOI: 10.1093/ehjcr/ytag265 PMID: 42065007

業績

2026年 論文一覧

Rare coding variant architecture and gene discovery from 130,000 sequenced cases of atrial fibrillation.

Simultaneous Tricuspid Valve Replacement and Left Bundle Branch Area Pacing With Surgical Lead Refixation.

Sex differences in circulating microRNA profiles in heart failure with preserved and reduced ejection fraction.

Association between baseline haptoglobin and early renal injury after pulsed-field ablation.

Standardized parallel pace-capture testing as a functional endpoint for lesion validation.

Efficacy and safety of a novel size-adjustable cryoballoon vs conventional cryoballoon: Results from the CONTRAST-CRYO II randomized clinical trial.

Two-Year Outcomes of Optical Coherence Tomography-Guided Percutaneous Coronary Intervention Stratified by Underlying Causes of Acute Coronary Syndrome.

Neurocognitive Function, Cerebral Blood Flow, and Hippocampal Volume After Catheter Ablation of Atrial Fibrillation.

Complexity Within Complexity: Defining the Anatomic Sweet Spot for OCT-Guided PCI.

Genetic variants and polygenic risk scores associated with paroxysmal atrial fibrillation in the Japanese population.

Virtual Noncontrast Images Derived From Photon-Counting CT Enhance Inter-Reader Reproducibility of Myocardial ECV Measurement in Patients With Cardiac Devices.

Distal Magnetic Sensors Eliminate Geometric Inaccuracy and Accelerate Mapping: A Preclinical Validation of a Novel Grid-Style Catheter.

Outpatient Cardiac Rehabilitation and Long-Term Clinical Outcomes After Transcatheter Aortic Valve Replacement.

Incidence and Predictors of Cardiac Tamponade in Contemporary Thermal Catheter Ablation of Atrial Fibrillation.

Extensive coronary venous system mapping for outflow tract ventricular arrhythmias: Utility of a dual over-the-wire microelectrode catheter technique.

Late dislodgement of a residual functional atrial lead 4 years after ventricular lead extraction: A case report.

Paced QRS morphology and lead location in left bundle branch area pacing assessed by photon-counting cardiac computed tomography.

Relationship of atherosclerotic lesion by optical coherence tomography with cholesterol efflux capacity by immobilized liposome-bound gel beads method.

Photon-Counting Detector Computed Tomography Depicts a Ventricular Tachycardia Substrate: Periaortic Septal Intramural Late Iodine Enhancement.

Ischaemic cardiomyopathy with a significant improvement in left ventricular wall motion following revascularization for a honeycomb-like structure of the left anterior descending artery: a case report.

2026年論文一覧